6 Best Red Dots for Glock 45 MOS

Join me in this Best Red Dots for Glock 45 MOS review.

The Glock 45 MOS combines the compact slide of a Glock 19 with the full-size frame of a Glock 17, making it a well-balanced platform ideal for duty, concealed carry, and tactical use.

To fully unlock its potential, adding a high-quality red dot sight can significantly enhance target acquisition speed, precision, and situational awareness.

Choosing the right optic, however, requires more than just finding one that fits. It involves evaluating key factors such as durability, battery life, reticle design, lens clarity, and ease of use, especially for a pistol that may see high-stress applications.

The best red dots for Glock 45 MOS deliver reliable performance under pressure, integrate seamlessly with the MOS platform, and offer intuitive features for everyday use or critical scenarios.

 

About the Glock 45 MOS

The Glock 45 MOS is a compact crossover pistol chambered in 9x19mm, blending a compact slide with a full-size frame to deliver the balanced performance of GLOCK’s Gen5 series.

Featuring the Modular Optic System (MOS), it allows for effortless reflex sight mounting without replacing the slide or adding external systems.

Developed from the proven G19X military platform and tailored to meet global law enforcement standards, the G45 MOS boasts front slide serrations for superior grip in adverse conditions, a subdued black frame, and a flared magwell for quick reloads.

Enhanced ergonomics include a smoother trigger pull, aggressive grip texturing, a reversible magazine catch, ambidextrous slide stop, and the customizable Modular Backstrap System.

The highly accurate GLOCK Marksman Barrel is at its core, making the G45 MOS a top-tier service pistol,reliable, adaptable, and built to perform when it matters most.

 

Best Red Dots for Glock 45 MOS

 

1) Holosun HS507C X2 Red Dot Sight

 

 

 

 

 

 

The Holosun HS507C X2 red dot sight is the best red dot for Glock 45 MOS, it comes packed with incredible features such as: long battery life (50000hrs), 12 brightness settings(10 DL & 2 NV ), unlimited eye relief, parallax free,solar failsafe and shake awake technology and more.

Designed specifically for full-sized pistols, the sight mounts using a standard RMR footprint, ensuring a secure and straightforward fit with the Glock’s MOS system. The package includes a T10 L key, CR1632 battery, lens cloth, and user manual, making installation and maintenance convenient right out of the box.

One of the key advantages of the HS507C X2 is its long-lasting Red Super LED, which delivers up to 50,000 hours of battery life. This optic also features a side-mounted battery tray, allowing quick battery changes without removing the sight or disturbing the zero.

Additionally, the Solar Failsafe system ensures that the sight remains operational even if the battery fails, adjusting reticle brightness automatically to match ambient lighting conditions. These features provide a high level of readiness and reliability in any environment.

The optic includes Holosun’s Multi-Reticle System, allowing users to toggle between a 2 MOA dot, a 32 MOA circle, or a combination of both. This flexibility makes target acquisition intuitive at close range while maintaining precision at distance.

The Shake Awake technology conserves battery life by powering down the LED when not in use and reactivating it with the slightest motion. The timing for sleep mode can be adjusted to match user preferences or disabled entirely for constant-on readiness.

Constructed from robust 7075 T6 aluminum and finished with a durable anodized coating, the HS507C X2 is built to handle tough conditions. It offers parallax-free operation, unlimited eye relief, and fine 1 MOA adjustments with ±50 MOA of travel for windage and elevation.

The optic is compatible with both daylight and night vision settings, offering ten daylight levels and two for NV devices. It’s 0.63×0.91-inch window provides a clear field of view without adding bulk to the slide.

Pros

• Long 50,000-hour battery life with side-access battery tray
• Solar Failsafe provides power redundancy
• Shake Awake technology with customizable sleep settings
• Multi-Reticle System for enhanced targeting flexibility
• Solid 7075 T6 aluminum housing with anodized finish
• Compatible with night vision devices
• Fits Glock 45 MOS using standard RMR footprint

Cons

• An open emitter design can be more susceptible to debris

 

2) Leupold DeltaPoint Pro Reflex Sight

 

 

 

 

 

The Leupold DeltaPoint Pro Red Dot Sight is a premium reflex sight that brings professional-grade clarity, rugged durability, and intuitive usability to the Glock 45 MOS. Built with Leupold’s Professional-Grade Red Dot Optical System, it delivers excellent light transmission and glare reduction, providing a crisp, clear sight picture even in harsh lighting.

This optic excels in both daylight and low-light environments, aided by a sharp illuminated reticle that helps shooters get on target quickly under pressure.

The DeltaPoint Pro features Motion Sensor Technology (MST), which conserves battery life by automatically deactivating the reticle after five minutes of inactivity. It reactivates the moment movement is detected, ensuring the sight is always ready when you draw.

Designed with usability in mind, the optic includes a top-mounted battery compartment, making battery changes simple and fast without removing the sight or breaking your zero. Precision click adjustments make it easy to fine-tune elevation and windage for consistent accuracy.

Crafted from aircraft-grade aluminum and reinforced with a steel sheath, the DeltaPoint Pro is built to endure harsh use and recoil from high-powered handguns. It has been thoroughly impact-tested, waterproofed, fogproofed, and rated to function in extreme temperatures from -40°F to 160°F. Leupold’s quality assurance process includes surviving 5,000 impacts on their recoil simulator—proof of its resilience in real-world conditions.

This optic also supports night vision devices with brightness settings that accommodate the sensitivity of modern NV equipment, extending its tactical capabilities.

Its large viewing window offers a broad field of view for fast target acquisition without sacrificing situational awareness, a major advantage in defensive scenarios or dynamic shooting environments.

Pros

• Excellent clarity and light transmission in all lighting conditions
• Motion Sensor Technology saves battery and ensures instant readiness
• Top-loading battery compartment for tool-free battery changes
• Large window and precise click adjustments for easy zeroing
• Built to withstand extreme temperatures, weather, and recoil
• Night vision compatible with adjustable brightness settings
• Made, machined, and assembled in the USA

Cons

• Short battery life

 

3) Trijicon RMR Type 2 Red Dot Sight

 

 

 

 

 

The Trijicon RMR Type 2 Adjustable LED Red Dot Sight is one of the best red dots for Glock 45 MOS. Its patented housing shape is designed to absorb and deflect impacts away from the lens, enhancing the optic’s ability to survive harsh conditions, recoil, and daily use. With a footprint compatible with most Glock MOS plates and aftermarket RMR mounts, this optic is a dependable upgrade for shooters who prioritize durability and reliability.

The RMR Type 2 is outfitted with upgraded electronics that are reinforced to handle the stresses of being mounted on slide ride pistols. It’s 3.25 MOA dot size offers a well-balanced aiming solution, large enough for fast acquisition and small enough for precision at longer ranges.

The true-color, multi-coated lens helps maintain an accurate view of the target area without adding any visual distortion, making it easier to focus under pressure.

One of the most user-friendly aspects of this optic is its illumination system. The Adjustable LED version allows users to switch between manual and automatic brightness modes using side-mounted buttons. Users can power down the optic for storage and, if left in manual mode, the RMR reverts to automatic mode after 16.5 hours to ensure it’s ready when needed.

For shooters who prefer to prevent accidental adjustments, the optic also includes a lock-out feature that restricts brightness control to automatic only. This version is night vision compatible, giving it added tactical versatility.

Built to endure the elements, the RMR Type 2 is waterproof up to 20 meters (66 feet), fogproof, and shockproof. Its ruggedized battery contacts and electronic systems are tested and proven to function reliably in extreme environments.

Backed by Trijicon’s warranty (15 years for the tritium lamp on dual-illuminated versions and 5 years for LED electronics), the RMR Type 2 is built to serve in demanding roles without compromise.

Pros

• Reinforced housing diverts stress away from the lens for added durability
• 3.25 MOA dot is ideal for both fast target acquisition and accuracy
• Manual and auto brightness modes with lock-out function
• Ruggedized electronics for reliability on slide-mounted pistols
• Waterproof up to 66 feet and compatible with night vision devices
• Multiple applications: pistol, rifle, shotgun, carbine
• No special tools needed for windage and elevation adjustments

Cons

• Premium price point compared to other micro red dots

 

4) HOLOSUN HE508T X2 Red Dot Sight

 

 

 

 

 

 

The Holosun HE508T X2 Red Dot Sight is a high-performance red dot sight designed for serious pistol use, making it a strong option for the Glock 45 MOS. It features a rugged Grade 5 titanium housing, offering superior strength and corrosion resistance without adding excessive weight to your slide.

Its RMR-compatible footprint allows seamless installation on Glock MOS platforms, especially when using a proper mounting plate. This optic is purpose-built for those who demand durability, battery longevity, and flexibility in a combat-ready configuration.

The HE508T X2 uses Holosun’s Red Super LED, providing up to 50,000 hours of runtime on a single CR1632 battery. A side-mounted battery tray allows for tool-free replacements while maintaining zero.

The Solar Failsafe feature adds redundancy by powering the sight using available light, ensuring the reticle remains visible even if the battery dies. Reticle brightness is also adjusted automatically when the optic is in auto mode, giving the user consistent visibility across varied lighting conditions.

This optic features Holosun’s Multi-Reticle System (MRS), which lets the shooter switch between a 2 MOA dot, a 32 MOA ring, or both simultaneously. The 32 MOA ring enables quicker target acquisition and is useful for close-quarters engagements, while the 2 MOA dot offers pinpoint accuracy at greater distances.

Shake Awake technology powers the sight down when idle, and instantly reactivates it with motion. Users can customize the sleep delay from 10 minutes to 12 hours, or turn the feature off entirely based on mission or carry needs.

Additional enhancements include Lock Mode, which prevents accidental adjustments by disabling the control buttons. With 10 daylight brightness settings and 2 night vision-compatible levels, the HE508T X2 adapts easily to bright outdoor environments or low-light tactical use.

The large viewing window (0.63×0.91 inches) provides a clear, unobstructed sight picture without excessive bulk, making it highly effective for both duty and concealed carry roles.

Pros

• Titanium housing for enhanced strength with a lightweight design
• The Multi-Reticle System allows switching between dot, ring, or both
• Solar Failsafe and Shake Awake extend battery life and reliability
• Lock Mode prevents accidental brightness or reticle changes
• RMR footprint fits standard Glock MOS mounting plates
• Night vision compatible with 12 total brightness levels
• Long battery life with easy-access side battery tray

Cons

• Requires a mounting plate for proper fit with the Glock 45 MOS

 

Also Consider

• HOLOSUN HE509T X2 Reflex Pistol Sight – Get it on Amazon 

 

5) Holosun HS407C-X2 Red Dot Sight

 

 

 

 

 

 

The Holosun HS407C X2 Red Dot Sight is a durable and reliable open reflex sight built for full-sized pistols like the Glock 45 MOS. Designed to deliver rapid target acquisition and consistent accuracy, it features a clean 2 MOA dot reticle and a wide window that helps shooters stay on target in high-stress situations.

The optic uses an industry-standard RMR footprint, making it a direct fit for Glock MOS platforms when paired with the appropriate mounting plate.

Built from 7075 T6 aluminum and finished with a durable anodized coating, the HS407C X2 is ready for rigorous field use. Holosun’s Red Super LED system offers up to 50,000 hours of battery life on a single CR1632 battery, housed in a side-mounted tray for quick replacement without dismounting the optic.

Solar Failsafe technology ensures a backup power source and automatically adjusts the dot’s brightness based on ambient light conditions when Auto Mode is active, keeping the reticle visible and balanced across changing environments.

The optic includes Shake Awake technology, which shuts off the LED after a preset period of inactivity and instantly reactivates it when movement is detected.

The delay can be customized from 10 minutes to 12 hours, depending on user preference, or can be completely disabled if constant-on readiness is needed. Lock Mode can also be activated to prevent unintentional changes to brightness or settings during concealed carry or tactical operations.

With ten daylight brightness settings and two night vision-compatible modes, the HS407C X2 adapts easily from bright daylight to low-light conditions.

The 2 MOA dot allows for precise shot placement without visual clutter, making it ideal for shooters who prefer simplicity and clarity in a defensive optic.

Pros

• A clear 2 MOA dot is ideal for precision shooting
• Solar Failsafe and Shake Awake increase reliability and battery efficiency
• Side battery tray enables easy replacement without dismounting
• Rugged 7075 T6 aluminum housing with wide viewing window
• Lock Mode prevents accidental setting changes
• Compatible with night vision (2 NV settings)
• Long battery life up to 50,000 hours

Cons

• Lacks the multi-reticle system found in other Holosun models

 

6) Aimpoint ACRO P-2 Red Dot Reflex Sight

 

 

 

 

 

 

Last on our best red dots for Glock 45 MOS list is the Aimpoint ACRO P-2 sight, a compact, fully enclosed red dot sight that brings unmatched ruggedness and consistent performance to the Glock 45 MOS. Engineered specifically for pistol applications, it uses a low-profile design and a secure mounting system to offer a streamlined fit on MOS-ready slides.

The ACRO P-2 features a 3.5 MOA red dot that balances speed and precision, providing fast target acquisition at close range while remaining accurate at distance.

One of the most important features of the ACRO P-2 is its fully enclosed housing, which protects the LED emitter and all internal components from water, dust, mud, and other environmental hazards.

Whether it’s rain, snow, or sand, the sealed optical channel maintains a clear sight picture in even the harshest conditions. The body is machined from high-strength 7075-T6 aluminum with a hard-anodized finish, making it impact-resistant and durable enough to handle duty or combat use.

The optic runs on a single CR2032 battery, delivering up to 50,000 hours (more than five years) of operation on setting 6. The battery can be replaced without removing the sight, preserving your zero and minimizing downtime.

With 10 total brightness settings,4 night vision compatible, and 6 daylight levels, the ACRO P-2 can adapt to any lighting condition, from bright sun to total darkness. Its parallax-free 1x magnification allows for both eyes open shooting and excellent situational awareness.

The ACRO P-2 is submersible up to 115 feet, making it one of the most water-resistant optics in its class. At just 2.1 oz, it adds minimal weight to your Glock while providing confidence-inspiring durability.

Although mounting plates are sold separately, many Glock 45 MOS users find it worth the investment for the enhanced sealing and reliability this optic provides.

Pros

• Fully enclosed housing protects against debris, moisture, and impact
• Long 50,000-hour battery life with easy-access battery compartment
• 3.5 MOA dot provides a good balance of speed and accuracy
• Compact and lightweight design optimized for pistol use
• Night vision compatible with 10 brightness settings
• Waterproof up to 115 feet (35 meters)
• Maintains zero through extreme shock and recoil

Cons

• Requires proprietary mounting plate for Glock 45 MOS

 

Next Read: 6 Best Red Dots for Glock 47 MOS

 

Factors to Consider when Choosing the Best Red Dots for Glock 45 MOS

When choosing the best red dot sight for the Glock 45 MOS, there are several important factors to consider that directly affect performance, reliability, and overall compatibility. Here are the key factors:

Durability and Build Quality

A red dot mounted on a pistol like the Glock 45 MOS must withstand the constant shock and vibration from repeated firing. Optics made from high-strength materials such as 7075-T6 aluminum or titanium offer increased resistance to impact and harsh environmental conditions.

The optic’s ability to resist water, fog, dust, and recoil is critical, especially for duty or concealed carry use where reliability is non-negotiable. Choosing a model that has been rigorously tested for ruggedness ensures long-term performance under stress.

Mounting Footprint and Compatibility

Not all red dot sights fit directly onto the Glock 45 MOS slide without an adapter plate. Understanding the optic’s mounting footprint, such as RMR, Docter/Noblex, or proprietary designs, is essential to ensure a proper and secure fit.

Some optics are ready to mount directly to the MOS system, while others require high-quality adapter plates. Using the correct interface prevents movement or loosening during recoil and helps maintain zero.

Reticle Style and Size

Red dot sights offer a variety of reticle options, including simple dots, circle-dot combinations, and adjustable multi-reticle systems. A 2 to 3.5 MOA dot size is generally preferred for balancing fast target acquisition and precision.

Smaller dots allow more precise aiming at longer distances, while larger ones are easier to pick up quickly in close-quarters engagements. Some users also benefit from reticle flexibility that allows toggling between different reticle styles depending on the task at hand.

Battery Life and Power Management

A red dot should offer long battery life to reduce the need for frequent replacements, especially in high-stress or self-defense scenarios. Features like motion-activated wake-up and automatic shutoff can greatly extend battery longevity.

Some models also incorporate solar backups to provide additional assurance. Side-loading battery compartments are a convenience, allowing changes without removing the sight or disturbing your zero.

Brightness Settings and Night Vision Compatibility

An optic with multiple brightness levels is important for adapting to different lighting conditions. The ability to adjust brightness manually or let it auto-regulate depending on ambient light ensures the reticle remains visible without being too dim or overly bright.

Night vision compatibility is a valuable feature for tactical users who operate in low-light environments with NV equipment.

Optical Clarity and Window Size

Clear glass with minimal distortion allows for a sharp, unobstructed sight picture. A larger window offers a wider field of view, which helps track moving targets and maintain situational awareness.

Optics that feature quality lens coatings and anti-glare properties also improve visibility in bright or variable lighting conditions. This contributes to both speed and confidence during target engagement.

Enclosed vs. Open Emitter Design

Red dot sights come in either open emitter or enclosed emitter configurations. Enclosed designs shield the LED and lens from dirt, moisture, and debris, making them better suited for extreme environments.

Open emitters tend to be lighter and provide a more open sight picture, but require more maintenance to stay clean. The choice depends on intended use and environmental exposure.

Ease of Use and Controls

Controls should be intuitive, responsive, and positioned so they can be easily accessed without interfering with the pistol’s function. Lock-out modes help prevent accidental brightness changes, especially during carry.

Clear click adjustments for windage and elevation make zeroing easier and more precise. Features that simplify setup and daily operation add to user confidence and operational efficiency.

Best Red Dots for Glock 45 MOS FAQs

Do I need an adapter plate to mount a red dot on the Glock 45 MOS?

Yes, most red dot sights require an adapter plate to mount securely to the Glock 45 MOS. The Glock Modular Optic System (MOS) is designed with a universal interface, but each optic may use a different footprint, such as RMR or ACRO, so it’s important to match your red dot to the correct plate.

Some optics come with adapter plates, while others require purchasing them separately. Using the correct plate ensures proper alignment, secure mounting, and consistent zero retention.

What is the ideal dot size for a red dot on the Glock 45 MOS?

A dot size of 2 MOA to 3.5 MOA is generally ideal for the Glock 45 MOS. A smaller dot allows for greater precision at extended distances, making it suitable for range use or competition.

A slightly larger dot improves visibility and speeds up target acquisition in close-quarters situations, which is beneficial for defensive or tactical use. The best size often depends on your shooting style and intended application, but many shooters prefer a balanced 3.25 MOA dot for versatility.

Is an enclosed emitter red dot better than an open emitter for the Glock 45 MOS?

Both types have their advantages, but enclosed emitter designs offer more protection against dirt, water, and debris, making them especially useful in harsh environments or for duty use.

Open emitter sights tend to be lighter and provide a broader field of view, which some users prefer for everyday carry or competition. If your Glock 45 MOS will be exposed to rain, mud, or extreme conditions, an enclosed emitter may be the more reliable option for long-term use.

Conclusion

After evaluating multiple optics based on durability, performance, and compatibility with the Glock 45 MOS, a few models stand out above the rest. The Trijicon RMR Type 2 remains a trusted choice for its battle-tested durability and versatile 3.25 MOA dot. The Aimpoint ACRO P-2 sets the benchmark for enclosed emitter designs, offering outstanding environmental protection and dependable battery life. Meanwhile, the Holosun HE508T X2 impresses with its titanium housing, multi-reticle system, and feature-rich configuration at a competitive price.

Whether you prioritize toughness, clarity, or customization, the best red dots for Glock 45 MOS deliver the reliability and precision the Glock 45 MOS deserves.